H2BP8

Across TCGA patient cohorts, H2BP8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,638 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible H2BP8-associated GO terms across cancer lineages are Pyruvate metabolic process, Regulation of mitochondrial fusion, and Mitochondrial fission. Each is linked with H2BP8 in more than 4 cancer types. Because this analysis shows association rather than direction, both H2BP8-to-partner and partner-to-H2BP8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pyruvate metabolic process grouped by H2BP8-low versus H2BP8-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BP8→partner) and Y-score (partner→H2BP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Pyruvate metabolic process →	+0.074	+0.052	<.001	.002	3	5
HNSC	Regulation of mitochondrial fusion →	+0.041	+0.018	<.001	<.001	3	4
STAD	Mitochondrial fission →	+0.074	+0.047	<.001	.001	3	4
STAD	Endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.080	+0.024	<.001	.005	3	4
STAD	Regulation of lipid localization →	+0.055	+0.028	<.001	.001	3	4
STAD	Response to leukemia inhibitory factor →	+0.069	+0.036	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,638 associations by consensus.

Pyruvate metabolic process by H2BP8 expression — STAD

Explore this box plot interactively →