PPP1R36

Across TCGA cell cohorts, PPP1R36 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PPP1R36-associated genes across cancer lineages are MYL2, TMC1, and WFDC12. Each is linked with PPP1R36 in more than 1 cancer types. Because this analysis shows association rather than direction, both PPP1R36-to-partner and partner-to-PPP1R36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYL2 grouped by PPP1R36-low versus PPP1R36-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R36→partner) and Y-score (partner→PPP1R36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MYL2 →	+0.379	+3.567	<.001	.003	3	1
BLOOD_Leukemia	TMC1 →	+0.344	+3.926	<.001	.003	3	1
BLOOD_Leukemia	WFDC12 →	+0.163	+3.289	<.001	.009	3	1
BLOOD_Leukemia	DEFB4A →	+0.078	+3.684	.005	.004	3	1
BLOOD_Leukemia	DSG4 →	+0.027	+3.684	<.001	.004	3	1
BLOOD_Leukemia	OR56A4 →	+0.007	+3.289	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

MYL2 by PPP1R36 expression — BLOOD_Leukemia

Explore this box plot interactively →