PPP1R36

Across TCGA pan-cancer cohorts, PPP1R36 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated PPP1R36 data layer compared with 3 for mutation status.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher PPP1R36 RNA is associated with better overall survival. In most high-consensus cancer types, elevated PPP1R36 expression acts as an unfavorable survival marker, although some lineages such as BRCA and KIRP show a favorable association.

BRCA, BLCA, and KIRC are the cancer types where PPP1R36 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.948	0.899	<.001	68	view →
BLCA	DFS	Tertile	IV	0.148	0.391	.001	62	view →
KIRC	DFS	Tertile	IV	0.337	0.608	.004	62	view →
LGG	DFS	Median	All	0.635	0.826	<.001	48	view →
KIRP	DFS	Median	All	0.954	0.863	.002	44	view →
MESO	DFS	Median	All	0.443	0.281	.003	30	view →
SARC	OS	Quartile	All	0.912	0.756	.002	20	view →
UCS	OS	Quartile	III,IV	0.243	0.648	.038	18	view →
UCEC	OS	Median	All	0.703	0.651	.021	16	view →
SCLC	DFS	Quartile	All	0.450	1.000	.004	15	view →
THYM	DFS	Quartile	All	0.633	1.000	.006	15	view →
LIHC	OS	Tertile	All	0.429	0.620	.009	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

PPP1R36–BRCA (OS)

Open the BRCA breakdown →