PPP1R1B

Across TCGA patient cohorts, PPP1R1B protein abundance is significantly associated with the RNA expression of many other genes, with 7,905 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PPP1R1B-associated genes across cancer lineages are SLC5A1, FMO5, and NR3C2. Each is linked with PPP1R1B in more than 4 cancer types. Because this analysis shows association rather than direction, both PPP1R1B-to-partner and partner-to-PPP1R1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PPP1R1B versus SLC5A1 in BRCA, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP1R1B→partner) and Y-score (partner→PPP1R1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SLC5A1 →	+1.479	+0.816	<.001	<.001	3	4
LUAD	FMO5 →	+0.996	+0.689	.005	.003	2	5
LSCC	NR3C2 →	+0.920	+0.573	<.001	.001	3	4
UCEC	NOSTRIN →	+0.929	+1.485	<.001	<.001	3	4
OV	MSC-AS1 →	-0.407	-0.709	.003	.006	3	4
LSCC	AZGP1 →	+2.159	+0.651	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,905 associations by consensus.

PPP1R1B vs SLC5A1 — BRCA

Explore this scatter interactively →