POLDIP3

Across TCGA patient cohorts, POLDIP3 mutation is significantly associated with the RNA expression of many other genes, with 2,727 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible POLDIP3-associated genes across cancer lineages are RN7SL554P, RNU6-1228P, and TEMN3-AS1. Each is linked with POLDIP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both POLDIP3-to-partner and partner-to-POLDIP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL554P grouped by POLDIP3-low versus POLDIP3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (POLDIP3→partner) and Y-score (partner→POLDIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL554P →	+0.100	+4.614	<.001	.006	3	2
UCEC	RNU6-1228P →	+0.120	+3.464	.008	.002	3	2
UCEC	TEMN3-AS1 →	+0.180	+2.464	<.001	.007	3	2
SKCM	SFPQP1 →	+0.112	+3.661	<.001	.009	3	2
BLCA	PSAT1P4 →	+0.068	+4.038	<.001	.002	3	2
BLCA	MTCO3P2 →	+0.162	+3.628	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,727 associations by consensus.

RN7SL554P by POLDIP3 expression — SKCM

Explore this box plot interactively →