Q-omics provides the consensus-scored SFPQP1 profile across patient tissues and cancer cell-line models. SFPQP1 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in STAD. Among the 18 cancer types available for tumor–normal comparison, SFPQP1 is differentially expressed in 2, with the highest sampling consensus in COAD. Additionally, SFPQP1 RNA expression shows 5,149 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight STAD, and COAD as cancer lineages where SFPQP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for SFPQP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes SFPQP1 survival associations across molecular data types. SFPQP1 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible SFPQP1 RNA expression–survival associations across cancer types. High SFPQP1 expression shows unfavorable associations in LIHC, READ, GBM and SKCM, but favorable associations in STAD and BLCA. The STAD Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .023). Together, the overview and detailed table identify STAD as the clearest survival context for SFPQP1 RNA expression.
This table summarizes SFPQP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for SFPQP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. SFPQP1 shows lower tumor expression in KIRC and higher tumor expression in COAD. The COAD box plot shows higher SFPQP1 RNA expression in tumor versus normal tissue (log2 FC = +0.032, t-test p = .012).
This table shows molecular features associated with SFPQP1 in patient tissues and cancer cell lines. In patient samples, SFPQP1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
