PLEKHG4B

Across TCGA patient cohorts, PLEKHG4B RNA expression is significantly associated with the protein abundance of many other proteins, with 9,123 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PLEKHG4B-associated proteins across cancer lineages are WDR70, MTA1_S576, and FSTL1. Each is linked with PLEKHG4B in more than 4 cancer types. Because this analysis shows association rather than direction, both PLEKHG4B-to-partner and partner-to-PLEKHG4B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PLEKHG4B versus WDR70 in UCEC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PLEKHG4B→partner) and Y-score (partner→PLEKHG4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	WDR70 →	+0.300	+0.919	.001	.001	3	5
LSCC	MTA1_S576 →	+0.587	+0.980	.003	<.001	3	4
OV	FSTL1 →	+0.710	+1.201	.001	.003	3	4
HNSC	RCN2 →	+0.515	+0.955	<.001	.006	3	4
BRCA	RETSAT →	-0.497	-1.243	<.001	<.001	3	4
BRCA	SF3B2 →	+0.162	+0.991	.002	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,123 associations by consensus.

PLEKHG4B vs WDR70 — UCEC

Explore this scatter interactively →