PINK1-AS

Across TCGA patient cohorts, PINK1-AS RNA expression is significantly associated with the mutation status of many other genes, with 8,771 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PINK1-AS-associated genes across cancer lineages are TP53, PTPRD, and AHNAK2. Each is linked with PINK1-AS in more than 4 cancer types. Because this analysis shows association rather than direction, both PINK1-AS-to-partner and partner-to-PINK1-AS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by PINK1-AS-low versus PINK1-AS-high in SKCM.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PINK1-AS→partner) and Y-score (partner→PINK1-AS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TP53 →	+2.288	+0.356	<.001	<.001	3	5
STAD	PTPRD →	+2.247	+0.487	.005	<.001	3	5
STAD	AHNAK2 →	+1.609	+0.433	.002	<.001	3	5
STAD	FCGBP →	+3.338	+0.500	.004	<.001	3	5
STAD	NAV3 →	+1.971	+0.438	<.001	<.001	3	5
COAD	DNAH10 →	+2.112	+0.443	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,771 associations by consensus.

TP53 by PINK1-AS expression — SKCM

Explore this box plot interactively →