PIGB

Across TCGA patient cohorts, PIGB protein abundance is significantly associated with the RNA expression of many other genes, with 1,638 significant associations in total. OV shows the largest number of these associations.

The most reproducible PIGB-associated genes across cancer lineages are SLC17A7, RNU6-933P, and NYNRIN. Each is linked with PIGB in more than 1 cancer types. Because this analysis shows association rather than direction, both PIGB-to-partner and partner-to-PIGB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PIGB versus SLC17A7 in PDAC, with a Pearson correlation of -0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PIGB→partner) and Y-score (partner→PIGB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SLC17A7 →	-0.101	-0.490	.001	.003	3	2
LUAD	RNU6-933P →	-1.887	-0.397	.002	.001	3	2
OV	NYNRIN →	-1.528	-0.587	<.001	.001	3	2
CCRCC	SCTR →	+1.426	+0.663	.004	.002	3	2
PDAC	LINC02477 →	+0.376	+0.705	<.001	<.001	3	2
LUAD	CASP6 →	+0.605	+0.245	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,638 associations by consensus.

PIGB vs SLC17A7 — PDAC

Explore this scatter interactively →