PHBP21

Across TCGA patient cohorts, PHBP21 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,747 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PHBP21-associated proteins across cancer lineages are LARP1_T299, PBRM1_S1453, and TRIM29_S489. Each is linked with PHBP21 in more than 3 cancer types. Because this analysis shows association rather than direction, both PHBP21-to-partner and partner-to-PHBP21 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PHBP21 versus LARP1_T299 in OV, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PHBP21→partner) and Y-score (partner→PHBP21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LARP1_T299 →	+0.807	+1.076	<.001	<.001	3	3
LUAD	PBRM1_S1453 →	-1.043	-0.426	<.001	.004	3	3
BRCA	TRIM29_S489 →	+1.071	+0.879	<.001	<.001	3	3
GBM	PHLDA3 →	+0.574	+0.454	.003	.009	2	4
OV	OPHN1_S652 →	-0.620	-1.015	<.001	<.001	3	3
LUAD	RRM2B →	+0.448	+0.446	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,747 associations by consensus.

PHBP21 vs LARP1_T299 — OV

Explore this scatter interactively →