PDE6H

Across TCGA patient cohorts, PDE6H RNA expression is significantly associated with the protein abundance of many other proteins, with 7,011 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PDE6H-associated proteins across cancer lineages are APBA1_S263, NPDC1_S236, and MSN. Each is linked with PDE6H in more than 2 cancer types. Because this analysis shows association rather than direction, both PDE6H-to-partner and partner-to-PDE6H results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PDE6H versus APBA1_S263 in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PDE6H→partner) and Y-score (partner→PDE6H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	APBA1_S263 →	+0.558	+0.294	<.001	<.001	3	3
GBM	NPDC1_S236 →	+1.500	+0.433	<.001	<.001	3	3
UCEC	MSN →	+0.246	+0.307	<.001	.009	3	3
OV	MRPS14 →	-0.303	-0.133	.003	.004	3	3
CCRCC	PSMD3 →	-0.128	-0.197	.001	.001	3	2
CCRCC	QSOX1_S426 →	+1.161	+0.230	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,011 associations by consensus.

PDE6H vs APBA1_S263 — GBM

Explore this scatter interactively →