PCDHA10

Across TCGA cell cohorts, PCDHA10 mutation is significantly associated with the RNA expression of many other genes, with 869 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PCDHA10-associated genes across cancer lineages are NDC80, GPR148, and C5orf52. Each is linked with PCDHA10 in more than 2 cancer types. Because this analysis shows association rather than direction, both PCDHA10-to-partner and partner-to-PCDHA10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NDC80 grouped by PCDHA10-low versus PCDHA10-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCDHA10→partner) and Y-score (partner→PCDHA10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	NDC80 →	+0.642	+2.545	<.001	<.001	3	3
LUNG_NSCLC_LUAD	GPR148 →	+0.023	+4.665	<.001	<.001	3	2
LUNG_NSCLC_LUAD	C5orf52 →	+0.076	+4.228	<.001	<.001	3	2
BLOOD_Leukemia	RAD1 →	+0.481	+3.259	.004	.006	3	2
LARGE_INTESTINE	RPA2 →	+0.424	+2.129	.007	.001	3	2
BLOOD_Leukemia	KIF14 →	+0.814	+3.199	.004	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 869 associations by consensus.

NDC80 by PCDHA10 expression — LARGE_INTESTINE

Explore this box plot interactively →