PCDHA10

Across TCGA pan-cancer cohorts, PCDHA10 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated PCDHA10 data layer compared with 11 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher PCDHA10 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated PCDHA10 expression acts as an unfavorable survival marker, although some lineages such as UVM and UCS show a favorable association.

LUSC, UVM, and UCS are the cancer types where PCDHA10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Median	All	0.561	0.727	<.001	103	view →
UVM	OS	Median	All	0.806	0.443	<.001	102	view →
UCS	DFS	Median	II,III,IV	0.516	0.203	.002	58	view →
STAD	OS	Tertile	All	0.627	0.779	.002	51	view →
TGCT	DFS	Median	All	0.711	0.884	.007	16	view →
COAD	DFS	Median	II,III,IV	0.708	0.793	.007	14	view →
SKCM	OS	Tertile	IV	1.000	0.179	.014	13	view →
KIRC	OS	Tertile	All	0.904	0.846	.015	13	view →
HNSC	OS	Median	III,IV	0.180	0.373	.014	13	view →
BLCA	DFS	Quartile	All	0.551	0.681	.018	10	view →
CHOL	DFS	Median	All	0.135	0.749	.003	9	view →
SCLC	OS	Tertile	II,III,IV	0.343	0.689	.023	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

PCDHA10–LUSC (DFS)

Open the LUSC breakdown →