PCBP1-AS1

Across TCGA patient cohorts, PCBP1-AS1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PCBP1-AS1-associated genes across cancer lineages are IGHD1-26, RPL23AP4, and ATF4P1. Each is linked with PCBP1-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PCBP1-AS1-to-partner and partner-to-PCBP1-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGHD1-26 grouped by PCBP1-AS1-low versus PCBP1-AS1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PCBP1-AS1→partner) and Y-score (partner→PCBP1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGHD1-26 →	+1.391	+4.484	<.001	.009	3	1
UCEC	RPL23AP4 →	+0.301	+5.302	<.001	.001	3	1
UCEC	ATF4P1 →	+0.183	+5.302	<.001	.001	3	1
UCEC	SFPQP1 →	+0.083	+4.326	.001	.007	3	1
UCEC	RPS12P18 →	+0.571	+4.233	<.001	.009	3	1
UCEC	RPL23AP72 →	+0.561	+4.374	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

IGHD1-26 by PCBP1-AS1 expression — UCEC

Explore this box plot interactively →