PCBP1-AS1

Across TCGA pan-cancer cohorts, PCBP1-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated PCBP1-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher PCBP1-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated PCBP1-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BLCA show a favorable association.

HNSC, ACC, and BLCA are the cancer types where PCBP1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	IV	0.496	0.271	<.001	125	view →
ACC	DFS	Median	All	0.199	0.687	<.001	112	view →
BLCA	OS	Median	All	0.529	0.350	<.001	101	view →
BRCA	OS	Quartile	III,IV	0.964	0.797	.001	51	view →
LGG	DFS	Median	All	0.660	0.810	<.001	44	view →
READ	OS	Quartile	II,III,IV	0.816	0.259	<.001	39	view →
LUAD	DFS	Quartile	II,III,IV	0.555	0.272	.005	37	view →
PAAD	OS	Quartile	All	0.574	0.317	.015	34	view →
DLBC	DFS	Tertile	All	0.609	0.912	.020	23	view →
MESO	OS	Quartile	II,III,IV	0.630	0.321	.003	21	view →
CESC	OS	Median	All	0.854	0.736	.004	20	view →
PRAD	DFS	Tertile	All	0.826	0.934	.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

PCBP1-AS1–HNSC (DFS)

Open the HNSC breakdown →