P2RX6

Across TCGA patient cohorts, P2RX6 protein abundance is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible P2RX6-associated genes across cancer lineages are CIZ1, OTOS, and KMT2C. Each is linked with P2RX6 in more than 1 cancer types. Because this analysis shows association rather than direction, both P2RX6-to-partner and partner-to-P2RX6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, P2RX6 versus CIZ1 in UCEC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (P2RX6→partner) and Y-score (partner→P2RX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CIZ1 →	+0.796	+0.575	.009	.008	3	1
UCEC	OTOS →	+1.216	+0.857	.003	.007	3	1
UCEC	KMT2C →	+1.042	+0.673	.001	.005	3	1
UCEC	RNU7-133P →	+3.281	+0.848	.001	.008	2	1
UCEC	LINC01259 →	+0.440	+0.837	.001	.003	2	1
UCEC	MIR5190 →	+2.905	+0.657	.007	.007	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

P2RX6 vs CIZ1 — UCEC

Explore this scatter interactively →