Q-omics provides the consensus-scored MIR5190 profile across patient tissues and cancer cell-line models. MIR5190 expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in TGCT. Among the 18 cancer types available for tumor–normal comparison, MIR5190 is differentially expressed in 4, with the highest sampling consensus in UCEC. Additionally, MIR5190 RNA expression shows 9,221 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight TGCT, UCEC, and LSCC as cancer lineages where MIR5190 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR5190 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR5190 survival associations across molecular data types. MIR5190 RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR5190 RNA expression–survival associations across cancer types. High MIR5190 expression shows unfavorable associations in TGCT, KICH, OV and SKCM, but favorable associations in LAML and LUAD. The TGCT Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify TGCT as the clearest survival context for MIR5190 RNA expression.
This table summarizes MIR5190 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in UCEC for RNA.
This table ranks reproducible tumor–normal expression differences for MIR5190. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR5190 shows lower tumor expression in UCEC and LUSC and higher tumor expression in HNSC and LIHC. The UCEC box plot shows higher MIR5190 RNA expression in normal versus tumor tissue (log2 FC = −0.622, t-test p = .043).
This table shows molecular features associated with MIR5190 in patient tissues and cancer cell lines. In patient samples, MIR5190 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set.
