OTX2P1

Across TCGA patient cohorts, OTX2P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,218 significant associations in total. STAD shows the largest number of these associations.

The most reproducible OTX2P1-associated GO terms across cancer lineages are Positive regulation of apoptotic signaling pathway, Protein folding, and Nucleoside triphosphate metabolic process. Each is linked with OTX2P1 in more than 8 cancer types. Because this analysis shows association rather than direction, both OTX2P1-to-partner and partner-to-OTX2P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of apoptotic signaling pathway grouped by OTX2P1-low versus OTX2P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OTX2P1→partner) and Y-score (partner→OTX2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of apoptotic signaling pathway →	+0.074	+0.160	<.001	<.001	3	9
STAD	Protein folding →	+0.081	+0.159	<.001	<.001	3	9
STAD	Nucleoside triphosphate metabolic process →	+0.083	+0.189	<.001	<.001	3	9
STAD	Positive regulation of membrane permeability →	+0.077	+0.156	<.001	<.001	3	8
ESCA	Calcium ion export across plasma membrane →	+0.057	+0.100	<.001	.003	2	9
STAD	Positive regulation of double-strand break repair via nonhomologous end joining →	+0.058	+0.156	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,218 associations by consensus.

Positive regulation of apoptotic signaling pathway by OTX2P1 expression — STAD

Explore this box plot interactively →