Q-omics provides the consensus-scored OTX2P1 profile across patient tissues and cancer cell-line models. OTX2P1 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, OTX2P1 is differentially expressed in 2, with the highest sampling consensus in THCA. Additionally, OTX2P1 RNA expression shows 6,218 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight ACC, THCA, and STAD as cancer lineages where OTX2P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for OTX2P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes OTX2P1 survival associations across molecular data types. OTX2P1 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible OTX2P1 RNA expression–survival associations across cancer types. High OTX2P1 expression shows unfavorable associations in ACC, STAD, BRCA, UCS, LIHC and KICH. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for OTX2P1 RNA expression.
This table summarizes OTX2P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for OTX2P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. OTX2P1 shows lower tumor expression in THCA and LUSC. The THCA box plot shows higher OTX2P1 RNA expression in normal versus tumor tissue (log2 FC = −0.072, t-test p < 0.001).
This table shows molecular features associated with OTX2P1 in patient tissues and cancer cell lines. In patient samples, OTX2P1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
