OR8D4

Across TCGA patient cohorts, OR8D4 mutation is significantly associated with the RNA expression of many other genes, with 238 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible OR8D4-associated genes across cancer lineages are SCYL1, SPATA31C1, and LINC02886. Each is linked with OR8D4 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR8D4-to-partner and partner-to-OR8D4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCYL1 grouped by OR8D4-low versus OR8D4-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR8D4→partner) and Y-score (partner→OR8D4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	SCYL1 →	+0.479	+3.268	.001	.008	3	2
LUSC	SPATA31C1 →	+0.231	+2.417	.001	.009	3	2
LUAD	LINC02886 →	+0.380	+3.143	<.001	.002	3	2
LUSC	LRRC37A13P →	+0.206	+2.487	<.001	.007	3	2
LUSC	MAGEA2 →	+0.241	+3.329	<.001	<.001	3	2
LUAD	SPZ1 →	+0.081	+2.805	.006	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 238 associations by consensus.

SCYL1 by OR8D4 expression — LUSC

Explore this box plot interactively →