OR52N1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, OR52N1 mutation is significantly associated with the RNA expression of many other genes, with 2,352 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR52N1-associated genes across cancer lineages are RNU6-796P, CYCTP, and MIR3925. Each is linked with OR52N1 in more than 2 cancer types. Because this analysis shows association rather than direction, both OR52N1-to-partner and partner-to-OR52N1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-796P grouped by OR52N1-low versus OR52N1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR52N1→partner) and Y-score (partner→OR52N1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCRNU6-796P →+0.201+3.326<.001.00533
LUSCCYCTP →+0.240+3.334.001<.00132
CESCMIR3925 →+0.572+6.144<.001.00132
SKCMHOMER1 →+0.772+2.597.001.00532
UCECPSMD6 →+0.433+3.386<.001.00432
UCECSTOML2 →+0.522+2.262.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,352 associations by consensus.

RNU6-796P by OR52N1 expression — LUSC

Box plot of RNU6-796P in OR52N1-low vs OR52N1-high samples in LUSC.

Explore this box plot interactively →

Exploration