OR4S1

Across TCGA patient cohorts, OR4S1 mutation is significantly associated with the RNA expression of many other genes, with 504 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible OR4S1-associated genes across cancer lineages are RFC3P1, CT83, and CDRT15P8. Each is linked with OR4S1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4S1-to-partner and partner-to-OR4S1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RFC3P1 grouped by OR4S1-low versus OR4S1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4S1→partner) and Y-score (partner→OR4S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RFC3P1 →	+0.023	+3.556	<.001	.001	3	2
COAD	CT83 →	+2.012	+4.321	<.001	.001	3	2
READ	CDRT15P8 →	+0.101	+5.421	<.001	.005	3	2
UCEC	UBXN6 →	+0.423	+2.606	.006	.006	3	2
UCEC	RNA5SP516 →	+0.232	+3.063	<.001	.007	3	2
UCEC	RNU6-376P →	+0.327	+3.579	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 504 associations by consensus.

RFC3P1 by OR4S1 expression — SKCM

Explore this box plot interactively →