OR4F15

Across TCGA patient cohorts, OR4F15 mutation is significantly associated with the RNA expression of many other genes, with 615 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR4F15-associated genes across cancer lineages are OR5I1, LDHAL6B, and MIR548AY. Each is linked with OR4F15 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR4F15-to-partner and partner-to-OR4F15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5I1 grouped by OR4F15-low versus OR4F15-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4F15→partner) and Y-score (partner→OR4F15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OR5I1 →	+0.023	+3.003	.001	.007	3	2
UCEC	LDHAL6B →	+0.420	+2.404	<.001	.004	3	2
READ	MIR548AY →	+0.602	+5.219	<.001	.006	3	2
UCEC	MIR378E →	+0.356	+3.231	<.001	.004	3	2
CESC	MIR4252 →	+0.919	+4.551	<.001	.004	3	2
LUSC	RNA5SP332 →	+0.184	+4.742	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 615 associations by consensus.

OR5I1 by OR4F15 expression — UCEC

Explore this box plot interactively →