OR4F15

Across TCGA pan-cancer cohorts, OR4F15 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated OR4F15 data layer compared with 5 for mutation status.

The strongest signal is observed in thyroid carcinoma (THCA), where higher OR4F15 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated OR4F15 expression acts as an unfavorable survival marker, although some lineages such as KIRP and OV show a favorable association.

THCA, UVM, and BLCA are the cancer types where OR4F15 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	All	0.220	0.953	<.001	168	view →
UVM	DFS	Tertile	All	0.426	0.824	<.001	123	view →
BLCA	DFS	Tertile	III,IV	0.297	0.556	.002	81	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	45	view →
LGG	DFS	Tertile	All	0.437	0.833	<.001	27	view →
SKCM	DFS	Quartile	III,IV	0.438	0.639	.009	20	view →
UCEC	DFS	Tertile	All	0.711	0.899	.026	18	view →
LIHC	DFS	Tertile	II,III,IV	0.044	0.427	<.001	18	view →
KIRP	DFS	Tertile	II,III,IV	1.000	0.428	.027	12	view →
PCPG	DFS	Tertile	All	0.088	0.846	.006	9	view →
KIRC	DFS	Tertile	IV	0.330	0.675	.015	6	view →
OV	DFS	Tertile	III,IV	0.545	0.149	.049	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

OR4F15–THCA (OS)

Open the THCA breakdown →