OR4E1

Across TCGA patient cohorts, OR4E1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,910 significant associations in total. STAD shows the largest number of these associations.

The most reproducible OR4E1-associated GO terms across cancer lineages are T cell receptor signaling pathway, Regulation of receptor-mediated endocytosis, and Lymphocyte apoptotic process. Each is linked with OR4E1 in more than 9 cancer types. Because this analysis shows association rather than direction, both OR4E1-to-partner and partner-to-OR4E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, T cell receptor signaling pathway grouped by OR4E1-low versus OR4E1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (OR4E1→partner) and Y-score (partner→OR4E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	T cell receptor signaling pathway →	+0.051	+0.042	<.001	<.001	3	10
STAD	Regulation of receptor-mediated endocytosis →	+0.048	+0.043	<.001	<.001	3	10
STAD	Lymphocyte apoptotic process →	+0.065	+0.053	<.001	<.001	3	10
STAD	Regulation of viral process →	+0.060	+0.062	<.001	.002	3	9
STAD	Extrinsic apoptotic signaling pathway →	+0.063	+0.040	<.001	<.001	3	9
STAD	T cell activation involved in immune response →	+0.044	+0.046	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,910 associations by consensus.

T cell receptor signaling pathway by OR4E1 expression — STAD

Explore this box plot interactively →