OR4E1

Across TCGA pan-cancer cohorts, OR4E1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR4E1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where OR4E1 RNA is repressed in tumor relative to normal tissue. In most cancer types OR4E1 is over-expressed in tumor, although a few such as THCA and COAD show the opposite, repressed pattern.

THCA and COAD are the cancer types where OR4E1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR4E1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	All	−0.010	.047	2	view →
COAD	Female	III,IV	−0.168	.012	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

OR4E1–THCA

Open the THCA breakdown →