Across TCGA patient cohorts, OR2A42 mutation is significantly associated with the RNA expression of many other genes, with 131 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible OR2A42-associated genes across cancer lineages are OR5D3P, MRPL35P1, and COX5BP8. Each is linked with OR2A42 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR2A42-to-partner and partner-to-OR2A42 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR2A42→partner) and Y-score (partner→OR2A42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OR5D3P →	+0.113	+6.917	<.001	<.001	3	1
COAD	MRPL35P1 →	+0.261	+5.017	<.001	.009	3	1
COAD	COX5BP8 →	+0.418	+5.893	<.001	.002	3	1
COAD	LINC02612 →	+0.129	+5.602	.004	.004	3	1
COAD	TUBB4BP5 →	+0.349	+5.693	.003	.003	3	1
COAD	CYCSP49 →	+0.327	+7.142	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 131 associations by consensus.

Exploration

OR2A42 survival (RNA) · tumor vs normal (RNA) · all OR2A42 data types