Across TCGA pan-cancer cohorts, OR2A42 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of OR2A42’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where OR2A42 RNA is repressed in tumor relative to normal tissue. In most cancer types OR2A42 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KICH, and LUAD are the cancer types where OR2A42 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR2A42 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	All	−0.228	<.001	8	view →
KICH	All	All	−0.059	.005	4	view →
LUAD	All	II,III,IV	−0.041	.021	4	view →
BRCA	All	All	−0.054	.006	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: OR2A42 RNA expression & survival · all OR2A42 data types