Across TCGA cell cohorts, OR10S1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible OR10S1-associated genes across cancer lineages are OR1Q1, APOC4, and ADAD1. Each is linked with OR10S1 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10S1-to-partner and partner-to-OR10S1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10S1→partner) and Y-score (partner→OR10S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR1Q1 →	+0.082	+3.760	<.001	.008	3	1
LUNG_NSCLC_LUAD	APOC4 →	+0.040	+4.681	<.001	.003	3	1
BLOOD_Lymphoma	ADAD1 →	+0.272	+5.169	<.001	.001	3	1
BLOOD_Lymphoma	OR52L1 →	+0.047	+4.191	.002	.007	3	1
LUNG_SCLC	RNASE1 →	+0.261	+3.252	.001	.009	3	1
LUNG_SCLC	SPRR1A →	+0.768	+2.830	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

OR10S1 survival (RNA) · tumor vs normal (RNA) · all OR10S1 data types