OR10A6

Across TCGA cell cohorts, OR10A6 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OR10A6-associated genes across cancer lineages are FAM71B, FOXI2, and FAM205C. Each is linked with OR10A6 in more than 1 cancer types. Because this analysis shows association rather than direction, both OR10A6-to-partner and partner-to-OR10A6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM71B grouped by OR10A6-low versus OR10A6-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OR10A6→partner) and Y-score (partner→OR10A6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FAM71B →	+0.003	+4.022	<.001	.006	3	1
LARGE_INTESTINE	FOXI2 →	+0.016	+3.632	<.001	.003	3	1
LARGE_INTESTINE	FAM205C →	+0.010	+4.022	<.001	.006	3	1
LARGE_INTESTINE	LY6L →	+0.091	+4.022	<.001	.006	3	1
LARGE_INTESTINE	H2BC3 →	+0.196	+3.196	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

FAM71B by OR10A6 expression — LARGE_INTESTINE

Explore this box plot interactively →