OR10A6

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, OR10A6 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of OR10A6’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where OR10A6 RNA is repressed in tumor relative to normal tissue. In most cancer types OR10A6 is over-expressed in tumor, although a few such as BRCA and KIRC show the opposite, repressed pattern.

BRCA and KIRC are the cancer types where OR10A6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in OR10A6 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
BRCAAllAll−0.033<.0016view →
KIRCAllAll−0.006.0095view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

OR10A6–BRCA

Tumor-vs-normal expression box plot for OR10A6 RNA in BRCA.

Open the BRCA breakdown →

Exploration