OPCML-IT2

Across TCGA patient cohorts, OPCML-IT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,514 significant associations in total. GBM shows the largest number of these associations.

The most reproducible OPCML-IT2-associated proteins across cancer lineages are RALGAPA1, RNF213, and RPS3A_S263. Each is linked with OPCML-IT2 in more than 2 cancer types. Because this analysis shows association rather than direction, both OPCML-IT2-to-partner and partner-to-OPCML-IT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, OPCML-IT2 versus RALGAPA1 in GBM, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OPCML-IT2→partner) and Y-score (partner→OPCML-IT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RALGAPA1 →	+0.277	+1.246	.001	.002	3	3
GBM	RNF213 →	-0.341	-1.257	<.001	.002	3	3
GBM	RPS3A_S263 →	-0.333	-1.303	.006	.004	3	3
GBM	CASP4 →	-0.375	-1.293	<.001	<.001	3	3
CCRCC	CSTA →	-0.719	-1.109	<.001	<.001	3	3
CCRCC	LILRB4_S319 →	-1.229	-1.900	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,514 associations by consensus.

OPCML-IT2 vs RALGAPA1 — GBM

Explore this scatter interactively →