Across TCGA patient cohorts, OPA1-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,070 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible OPA1-AS1-associated proteins across cancer lineages are GMPS, RFC5, and RIF1. Each is linked with OPA1-AS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both OPA1-AS1-to-partner and partner-to-OPA1-AS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (OPA1-AS1→partner) and Y-score (partner→OPA1-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GMPS →	+0.405	+0.861	<.001	<.001	3	5
HNSC	RFC5 →	+0.328	+0.760	<.001	<.001	3	4
LSCC	RIF1 →	+0.418	+0.730	<.001	<.001	3	4
LSCC	SDF2 →	+0.467	+0.775	.001	.005	3	4
LSCC	SIN3A →	+0.208	+0.843	.001	<.001	3	4
LSCC	CDYL →	+0.279	+0.559	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,070 associations by consensus.

Exploration

OPA1-AS1 survival (RNA) · tumor vs normal (RNA) · all OPA1-AS1 data types