OGFOD3

Across TCGA cell cohorts, OGFOD3 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible OGFOD3-associated genes across cancer lineages are AMELY, C10orf53, and HTR3D. Each is linked with OGFOD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both OGFOD3-to-partner and partner-to-OGFOD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AMELY grouped by OGFOD3-low versus OGFOD3-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OGFOD3→partner) and Y-score (partner→OGFOD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	AMELY →	+0.036	+5.415	<.001	.004	3	1
LARGE_INTESTINE	C10orf53 →	+0.012	+3.632	<.001	.003	3	1
BLOOD_Leukemia	HTR3D →	+0.014	+4.539	<.001	.007	3	1
BLOOD_Leukemia	RBMY1D →	+0.134	+4.539	<.001	.007	3	1
BLOOD_Leukemia	USP17L20 →	+0.004	+4.539	<.001	.007	3	1
BLOOD_Leukemia	USP17L18 →	+0.004	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

AMELY by OGFOD3 expression — SKIN

Explore this box plot interactively →