OGFOD3

Across TCGA cell cohorts, OGFOD3 mutation is significantly associated with the mutation status of many other genes, with 3,639 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible OGFOD3-associated genes across cancer lineages are RAB40C, MEX3D, and BACE2. Each is linked with OGFOD3 in more than 3 cancer types. Because this analysis shows association rather than direction, both OGFOD3-to-partner and partner-to-OGFOD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAB40C grouped by OGFOD3-low versus OGFOD3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (OGFOD3→partner) and Y-score (partner→OGFOD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	RAB40C →	+6.285	+5.560	<.001	<.001	1	4
LARGE_INTESTINE	MEX3D →	+2.459	+3.321	.005	.005	1	3
LARGE_INTESTINE	BACE2 →	+2.611	+4.372	<.001	<.001	1	3
LARGE_INTESTINE	SLIT3 →	+2.196	+4.015	.002	.002	1	3
BLOOD_Leukemia	MYT1L →	+3.063	+3.498	.006	.006	1	3
LARGE_INTESTINE	SHISA6 →	+3.459	+4.000	<.001	<.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,639 associations by consensus.

RAB40C by OGFOD3 expression — BLOOD_Leukemia

Explore this box plot interactively →