NT5C3B

Across TCGA cell cohorts, NT5C3B mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. CNS shows the largest number of these associations.

The most reproducible NT5C3B-associated genes across cancer lineages are IFNA2, MBD3L4, and LEUTX. Each is linked with NT5C3B in more than 1 cancer types. Because this analysis shows association rather than direction, both NT5C3B-to-partner and partner-to-NT5C3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA2 grouped by NT5C3B-low versus NT5C3B-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NT5C3B→partner) and Y-score (partner→NT5C3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	IFNA2 →	+0.019	+5.754	<.001	.002	3	1
CNS	MBD3L4 →	+0.022	+5.321	<.001	.005	3	1
CNS	LEUTX →	+0.129	+5.321	<.001	.005	3	1
CNS	KRTAP9-1 →	+0.090	+4.981	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

IFNA2 by NT5C3B expression — CNS

Explore this box plot interactively →