NRIP3

Across TCGA cell cohorts, NRIP3 mutation is significantly associated with the mutation status of many other genes, with 1,007 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NRIP3-associated genes across cancer lineages are DMTF1, PARP6, and OR4D6. Each is linked with NRIP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both NRIP3-to-partner and partner-to-NRIP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DMTF1 grouped by NRIP3-low versus NRIP3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NRIP3→partner) and Y-score (partner→NRIP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DMTF1 →	+4.309	+4.560	.007	.007	1	3
BLOOD_Leukemia	PARP6 →	+4.894	+4.894	.004	.004	1	3
BLOOD_Leukemia	OR4D6 →	+4.894	+4.894	.004	.004	1	2
BLOOD_Leukemia	MARS1 →	+3.309	+4.794	.002	.002	1	2
BLOOD_Leukemia	SF1 →	+3.479	+4.932	.002	.002	1	2
BLOOD_Leukemia	ETFDH →	+4.894	+4.894	.004	.004	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,007 associations by consensus.

DMTF1 by NRIP3 expression — BLOOD_Leukemia

Explore this box plot interactively →