NMD3

Across TCGA patient cohorts, NMD3 protein abundance is significantly associated with the RNA expression of many other genes, with 13,999 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NMD3-associated genes across cancer lineages are RFC4, MRPL47, and EEF1AKMT4. Each is linked with NMD3 in more than 7 cancer types. Because this analysis shows association rather than direction, both NMD3-to-partner and partner-to-NMD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NMD3 versus RFC4 in LSCC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMD3→partner) and Y-score (partner→NMD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC4 →	+0.803	+0.237	<.001	<.001	3	8
OV	MRPL47 →	+0.740	+0.289	<.001	.003	3	7
UCEC	EEF1AKMT4 →	+0.985	+0.234	<.001	.005	3	7
OV	SMC4 →	+1.065	+0.361	<.001	<.001	3	6
LUAD	KIF14 →	+0.782	+0.161	.002	.008	3	6
HNSC	ABCA8 →	-0.960	-0.298	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,999 associations by consensus.

NMD3 vs RFC4 — LSCC

Explore this scatter interactively →