NFATC4

Across TCGA cell cohorts, NFATC4 mutation is significantly associated with the RNA expression of many other genes, with 206 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NFATC4-associated genes across cancer lineages are FAM149A, IQCF5, and CRISP1. Each is linked with NFATC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NFATC4-to-partner and partner-to-NFATC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM149A grouped by NFATC4-low versus NFATC4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NFATC4→partner) and Y-score (partner→NFATC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FAM149A →	+1.768	+3.309	<.001	.006	3	2
BLOOD_Leukemia	IQCF5 →	+0.055	+4.201	<.001	<.001	3	2
LARGE_INTESTINE	CRISP1 →	+0.006	+2.415	<.001	.009	3	2
LARGE_INTESTINE	ELP5 →	+0.728	+2.743	<.001	.001	3	2
LARGE_INTESTINE	MT-ND2 →	-0.760	-3.395	<.001	.001	3	2
LARGE_INTESTINE	HERPUD1 →	+0.659	+2.043	.009	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 206 associations by consensus.

FAM149A by NFATC4 expression — BLOOD_Leukemia

Explore this box plot interactively →