Across TCGA patient cohorts, NELFA protein abundance is significantly associated with the RNA expression of many other genes, with 16,749 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NELFA-associated genes across cancer lineages are ZNF141, HAUS3, and RFC5. Each is linked with NELFA in more than 7 cancer types. Because this analysis shows association rather than direction, both NELFA-to-partner and partner-to-NELFA results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NELFA→partner) and Y-score (partner→NELFA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNF141 →	+0.527	+0.204	<.001	<.001	3	8
GBM	HAUS3 →	+0.424	+0.293	<.001	<.001	3	8
LSCC	RFC5 →	+0.633	+0.205	<.001	<.001	3	7
BRCA	MBTD1 →	+0.630	+0.220	<.001	<.001	2	8
HNSC	DCAF16 →	+0.976	+0.317	<.001	<.001	3	7
HNSC	MSL2 →	+0.631	+0.216	.009	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,749 associations by consensus.

Exploration

NELFA survival (RNA) · tumor vs normal (RNA) · all NELFA data types