Across TCGA pan-cancer cohorts, NELFA RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated NELFA data layer compared with 2 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher NELFA RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated NELFA expression acts as an unfavorable survival marker, although some lineages such as UCS and SCLC show a favorable association.

UCS, LIHC, and SCLC are the cancer types where NELFA RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	All	0.667	0.363	.003	82	view →
LIHC	DFS	Quartile	All	0.412	0.622	<.001	63	view →
SCLC	DFS	Median	All	0.990	0.538	.004	35	view →
PRAD	DFS	Tertile	All	0.725	0.859	.010	30	view →
KICH	OS	Tertile	III,IV	0.194	0.913	.004	27	view →
LUAD	DFS	Median	All	0.754	0.863	.008	16	view →
GBM	DFS	Quartile	All	0.326	0.171	.003	15	view →
SARC	OS	Quartile	All	0.595	0.900	.001	11	view →
LUSC	DFS	Quartile	III,IV	0.500	1.000	.008	10	view →
ACC	DFS	Tertile	IV	0.656	0.167	.024	9	view →
UVM	DFS	Tertile	All	0.300	0.905	.021	8	view →
STAD	DFS	Quartile	All	0.656	0.508	.034	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

Exploration

Same gene, other analysis: NELFA tumor-vs-normal RNA expression · all NELFA data types