NECTIN4-AS1

Across TCGA patient cohorts, NECTIN4-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,998 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NECTIN4-AS1-associated proteins across cancer lineages are NECTIN4, NECTIN4_S426, and S100A16. Each is linked with NECTIN4-AS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both NECTIN4-AS1-to-partner and partner-to-NECTIN4-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NECTIN4-AS1 versus NECTIN4 in LSCC, with a Pearson correlation of 0.85.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NECTIN4-AS1→partner) and Y-score (partner→NECTIN4-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	NECTIN4 →	+1.043	+1.393	<.001	<.001	3	7
LSCC	NECTIN4_S426 →	+1.398	+1.186	<.001	<.001	3	5
HNSC	S100A16 →	+0.541	+0.693	<.001	.007	3	5
BRCA	S100A11 →	+0.378	+0.365	<.001	<.001	3	5
HNSC	ZNF185 →	+0.890	+1.106	<.001	<.001	3	4
UCEC	TACSTD2 →	+0.636	+0.551	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,998 associations by consensus.

NECTIN4-AS1 vs NECTIN4 — LSCC

Explore this scatter interactively →