NDUFS7

Across TCGA cell cohorts, NDUFS7 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NDUFS7-associated genes across cancer lineages are ASPG, GUCA2A, and KHDC3L. Each is linked with NDUFS7 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFS7-to-partner and partner-to-NDUFS7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASPG grouped by NDUFS7-low versus NDUFS7-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFS7→partner) and Y-score (partner→NDUFS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ASPG →	+0.288	+3.803	<.001	.004	3	1
BLOOD_Leukemia	GUCA2A →	+0.026	+3.969	<.001	.009	3	1
BLOOD_Leukemia	KHDC3L →	+0.213	+4.096	<.001	.001	3	1
BLOOD_Leukemia	DPRX →	+0.076	+3.475	<.001	.006	3	1
BLOOD_Leukemia	IQCF5 →	+0.072	+4.201	<.001	.001	3	1
LARGE_INTESTINE	SSMEM1 →	+0.030	+3.707	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

ASPG by NDUFS7 expression — BLOOD_Leukemia

Explore this box plot interactively →