NDUFS7

Across TCGA pan-cancer cohorts, NDUFS7 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of NDUFS7’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where NDUFS7 RNA is repressed in tumor relative to normal tissue. In most cancer types NDUFS7 is over-expressed in tumor, although a few such as HNSC and KIRC show the opposite, repressed pattern.

HNSC, LIHC, and CHOL are the cancer types where NDUFS7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NDUFS7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	All	−0.468	<.001	10	view →
LIHC	Female	II,III,IV	+0.885	<.001	8	view →
CHOL	Female	All	+1.016	.002	2	view →
KIRC	Male	All	−0.311	.017	2	view →
KICH	All	All	+0.273	.025	2	view →
PRAD	All	All	−0.263	.002	2	view →
LUAD	All	All	−0.248	.004	2	view →
STAD	Male	All	−0.344	.041	1	view →
THCA	Male	II,III,IV	−0.334	.046	1	view →
LUSC	Male	All	+0.143	.029	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

NDUFS7–HNSC

Open the HNSC breakdown →