NDUFS7

Across TCGA pan-cancer cohorts, NDUFS7 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated NDUFS7 data layer compared with 7 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher NDUFS7 RNA is associated with better overall survival. In most high-consensus cancer types, elevated NDUFS7 expression acts as an unfavorable survival marker, although some lineages such as KIRP and CESC show a favorable association.

KIRP, CESC, and UCS are the cancer types where NDUFS7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	II,III,IV	0.742	0.297	.001	88	view →
CESC	DFS	Median	All	0.624	0.453	<.001	64	view →
UCS	OS	Median	IV	0.302	0.817	.002	58	view →
PAAD	DFS	Quartile	II,III,IV	0.563	0.347	.003	38	view →
KICH	DFS	Quartile	All	0.686	1.000	.014	20	view →
BRCA	DFS	Quartile	All	0.832	0.901	.014	17	view →
SCLC	OS	Quartile	All	0.810	0.475	.001	16	view →
READ	OS	Quartile	IV	0.611	0.931	.017	13	view →
DLBC	DFS	Tertile	All	0.938	0.687	.040	10	view →
LUSC	OS	Median	IV	0.255	0.851	.021	6	view →
CHOL	OS	Tertile	III,IV	0.948	0.208	.024	6	view →
HNSC	OS	Median	III,IV	0.785	0.701	.029	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

NDUFS7–KIRP (OS)

Open the KIRP breakdown →