Q-omics provides the consensus-scored NDUFB4P4 profile across patient tissues and cancer cell-line models. NDUFB4P4 expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, NDUFB4P4 is differentially expressed in 2, with the highest sampling consensus in HNSC. Additionally, NDUFB4P4 RNA expression shows 7,859 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight UVM, HNSC, and TGCT as cancer lineages where NDUFB4P4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for NDUFB4P4 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes NDUFB4P4 survival associations across molecular data types. NDUFB4P4 RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible NDUFB4P4 RNA expression–survival associations across cancer types. High NDUFB4P4 expression shows unfavorable associations in UVM, READ, THCA and ACC, but favorable associations in CESC and LUAD. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for NDUFB4P4 RNA expression.
This table summarizes NDUFB4P4 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for NDUFB4P4. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. NDUFB4P4 shows lower tumor expression in STAD and higher tumor expression in HNSC. The HNSC box plot shows higher NDUFB4P4 RNA expression in tumor versus normal tissue (log2 FC = +0.168, t-test p = .002).
This table shows molecular features associated with NDUFB4P4 in patient tissues and cancer cell lines. In patient samples, NDUFB4P4 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
