Across TCGA pan-cancer cohorts, NDUFB4P4 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of NDUFB4P4’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where NDUFB4P4 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NDUFB4P4 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.

HNSC and STAD are the cancer types where NDUFB4P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NDUFB4P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.168	.002	10	view →
STAD	Male	III,IV	−0.298	.009	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: NDUFB4P4 RNA expression & survival · all NDUFB4P4 data types