Q-omics provides the consensus-scored NBPF1 profile across patient tissues and cancer cell-line models. NBPF1 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, NBPF1 is differentially expressed in 11, with the highest sampling consensus in COAD. Additionally, NBPF1 RNA expression shows 20,200 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight ACC, and COAD as cancer lineages where NBPF1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for NBPF1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes NBPF1 survival associations across molecular data types. NBPF1 RNA expression shows survival associations in the most cancer types (24), followed by mutation status (2). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible NBPF1 RNA expression–survival associations across cancer types. High NBPF1 expression shows unfavorable associations in ACC, LUSC, LIHC and MESO, but favorable associations in KIRC and BRCA. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for NBPF1 RNA expression.
This table summarizes NBPF1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for NBPF1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. NBPF1 shows lower tumor expression in COAD, KICH, KIRC, THCA and READ and higher tumor expression in HNSC. The COAD box plot shows higher NBPF1 RNA expression in normal versus tumor tissue (log2 FC = −1.409, t-test p < 0.001).
This table shows molecular features associated with NBPF1 in patient tissues and cancer cell lines. In patient samples, NBPF1 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set. In cancer cell lines, NBPF1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BLOOD_Leukemia, while CRISPR and shRNA rows add functional-dependency signals in LARGE_INTESTINE.
