Across TCGA patient cohorts, NBPF1 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NBPF1-associated genes across cancer lineages are GATA6, JNK_pT183_Y185, and JNK2. Each is linked with NBPF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF1-to-partner and partner-to-NBPF1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF1→partner) and Y-score (partner→NBPF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GATA6 →	-0.170	-2.314	.028	.035	3	1
UCEC	JNK_pT183_Y185 →	-0.200	-3.169	.013	.019	3	1
UCEC	JNK2 →	+0.243	+3.009	.011	.019	3	1
UCEC	Ku80 →	+0.289	+2.472	.011	.011	3	1
UCEC	mTOR_pS2448 →	-0.201	-3.302	.005	.010	3	1
UCEC	p27_pT198 →	+0.167	+3.321	.001	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

NBPF1 survival (RNA) · tumor vs normal (RNA) · all NBPF1 data types