Across TCGA patient cohorts, NBPF1 mutation is significantly associated with the RNA expression of many other genes, with 691 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NBPF1-associated genes across cancer lineages are RNA5SP414, RNA5SP411, and RNA5SP412. Each is linked with NBPF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF1-to-partner and partner-to-NBPF1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF1→partner) and Y-score (partner→NBPF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNA5SP414 →	+0.143	+7.471	.001	.008	3	2
UCEC	RNA5SP411 →	+1.401	+2.393	<.001	.002	3	2
UCEC	RNA5SP412 →	+0.666	+2.552	<.001	.002	3	2
UCEC	RNA5SP416 →	+0.689	+2.376	<.001	.007	3	2
UCEC	RN7SL97P →	+0.128	+2.713	<.001	.002	3	2
UCEC	RNA5SP419 →	+0.895	+2.661	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 691 associations by consensus.

Exploration

NBPF1 survival (RNA) · tumor vs normal (RNA) · all NBPF1 data types